Staphylococcal scalded skin syndrome SSSS is an illness characterised by red blistering skin that looks like a burn or scald, hence its name staphylococcal scalded skin syndrome. SSSS is caused by the release of two exotoxins epidermolytic toxins A and B from toxigenic strains of the bacteria Staphylococcus aureus. Desmosomes are the part of the skin cell responsible for adhering to the adjacent skin cell.
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In both cases, the disease was reproduced by injections of staphylococci into mice. The adult patient, who had no other physical or laboratory abnormalities, showed intact humoral and cellular immunity; her uneventful clinical course was clearly different from the eight previously reported cases in adults. To our knowledge, the child represents the first case report of SSSS as a result of infection by a non-group 2 Staphylococcus.
This leaflet has been written to help you understand more about staphylococcal scalded skin syndrome. It tells you what it is, what causes it, what treatment is available, and where you can find out more about it. What is the staphylococcal scalded skin syndrome? Staphylococcal scalded skin syndrome is a widespread painful rash caused by a bacteria called Staphylococcus aureus, which produces a toxin that damages the outer layer of the skin causing it to be shed.
An year old female patient, with history of chronic obstructive pulmonary disease, was referred to our hospital with rash and septic shock. Nikolsky sign was elicited on patient's physical examination Fig. The patient died 24 h after admission, after having developed multiple organ dysfunction syndrome.
Initial symptoms can include fever usually low gradegeneralized redness, and tenderness of the skin. Onset of symptoms is usually rapid. Some individuals may experience nonspecific symptoms that develop before the skin symptoms including a sore throat and inflammation of the eyelids known as conjunctivitis.
Staphylococcal scalded skin syndrome SSSS is a systemic toxic disease whose symptoms include diffuse erythema and blister formation over the whole body 1. SSSS is ordinarily seen in children; in adults it is rare but serious 1. The patient had had immunosuppressive therapy for rheumatoid arthritis RA and was complicated with kidney failure associated with septic shock.
From the departments of medicine Drs. Rothenberg, Drew, and Feingold and dermatology Dr. An apparently healthy year-old man developed severe septicemia due to a phage group 2 Staphylococcus that was followed by a widespread, bullous eruption characterized by intraepidermal cleavage.
Staphylococcal scalded skin syndrome SSSS is an acute epidermolysis caused by a staphylococcal toxin. Infants and children are most susceptible. Symptoms are widespread bullae with epidermal sloughing.